Use of intralesional voriconazole for the treatment of cutaneous Scedosporium apiospermum infection.
نویسندگان
چکیده
Reprints or correspondence: Dr Dimitrios P. Kontoyiannis, Dept of Infectious Diseases, Infection Control and Employee Health, Unit 402, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030 (dkontoyi@ mdanderson.org). Clinical Infectious Diseases 2010; 51(2):254–255 2010 by the Infectious Diseases Society of America. All rights reserved. 1058-4838/2010/5102-0024$15.00 DOI: 10.1086/653685
منابع مشابه
Use of voriconazole in treatment of Scedosporium apiospermum infection: case report.
We report a case of disseminated Scedosporium apiospermum infection in a neutropenic patient with acute myeloid leukemia. Due to progression of the mycosis after 7 days of amphotericin B lipid complex therapy and to high susceptibility of the mold to voriconazole in vitro, the patient was treated with intravenous voriconazole. After a few days of therapy, fever disappeared and skin lesions impr...
متن کاملScedosporium apiospermum infections and the role of combination antifungal therapy and GM-CSF: A case report and review of the literature
Scedosporium apiospermum, a ubiquitous environmental mold, is increasingly reported as causing invasive fungal disease in immunocompromised hosts. It poses a therapeutic challenge due to its intrinsic resistance to traditional antifungals and ability to recur despite demonstrating susceptibility. We present an immunocompromised patient with a cutaneous S. apiospermum infection that disseminated...
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Opportunistic fungal infections are increasingly common in patients who undergo hematopoietic stem cell transplant (HSCT). Voriconazole is frequently used in allogeneic SCT recipients who receive immunosuppressant therapy for graft versus host disease to prevent invasive aspergillosis. Indications for voriconazole use include invasive aspergillosis, candidemia, Scedosporium apiospermum infectio...
متن کاملCombination Antifungal Therapy in the Treatment of Scedosporium apiospermum Central Nervous System Infections
Treatment of Scedosporium apiospermum central nervous system (CNS) infection typically consists of an azole in combination with surgical debridement. This approach requires prolonged treatment and carries a high associated mortality. We present two cases of the successful treatment of S. apiospermum CNS infections with the combination of voriconazole and terbinafine.
متن کاملSuccessful treatment of Scedosporium apiospermum soft tissue abscess with caspofungin and voriconazole in a severely immunocompromised patient with acute myeloid leukemia.
We report the case of a 53-year-old female patient with refractory acute myeloid leukemia developing a necrotic, soft tissue abscess on the right forearm caused by Scedosporium apiospermum during prolonged severe neutropenia (absolute white blood cell count <500/μL for 49 days). In the context of the severely immunocompromised state of the patient and her need for allogeneic hematopoietic stem ...
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ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 51 2 شماره
صفحات -
تاریخ انتشار 2010